Long-term tolerability of etoricoxib in patients with previous reactions to non-steroidal anti-inflammatory drugs.
نویسندگان
چکیده
Non-steroidal anti-inflammatory drugs frequently cause adverse reactions. This retrospective study was based on analysis of the data obtained from interviews conducted with 173 patients, who underwent and tolerated a challenge test with etoricoxib (a selective cyclooxigenase 2 enzyme inhibitor). Only one of 82 patients who were treated with etoricoxib reported reactions. We can conclude that etoricoxib shows a high long-term tolerability in patients with non-steroidal anti-inflammatory drug hypersensitivity.
منابع مشابه
Long-term tolerability of etoricoxib in different types of NSAID-intolerant subjects.
BACKGROUND Non-steroidal anti-inflammatory drugs (NSAIDs) are a frequent cause of hypersensitivity reactions, therefore, in clinical practice, it's important to find safe and effective substances. OBJECTIVE To evaluate the tolerability of etoricoxib and its subsequent actual use and safety at home. METHODS Etoricoxib tolerance was assessed by single-blind-placebo-controlled oral challenges ...
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Nonsteroidal antiinflammatory drugs (NSAIDs), including selective cyclooxygenase (COX)-2 inhibitors, have come to play an important role in the pharmacologic management of arthritis and pain. Clinical trials have established the efficacy of etoricoxib in osteoarthritis, rheumatoid arthritis, acute gouty arthritis, ankylosing spondylitis, low back pain, acute postoperative pain, and primary dysm...
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BACKGROUND The use of selective cyclooxygenase (COX) 2 inhibitors as an alternative to aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) has been suggested for patients with aspirin-exacerbated respiratory disease (AERD). OBJECTIVE To evaluate tolerability to etoricoxib, a second-generation COX-2 inhibitor with high in vitro selectivity for COX-2 in patients with AERD. METHODS...
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عنوان ژورنال:
- International journal of immunopathology and pharmacology
دوره 22 4 شماره
صفحات -
تاریخ انتشار 2009